2021

• Li S, Bonner JN, Wan B, So S, Summers A, Gonzalez L, Xue X#, Xiaolan Zhao#. Esc2 orchestrates substrate-specific sumoylation by acting as a SUMO E2 cofactor in genome maintenance. Genes Dev. 2021, 35(3-4): 261-272.

2020

• Lisby M#, Xue X#. Protocol for Purification of Human ZGRF1 and Its Regulatory Function on RAD51-Mediated D-Loop Formation. STAR Protoc. 2020 Sep 18;1(2). doi: 10.1016/j.xpro.2020.100099. Epub 2020 Sep 1. PubMed PMID: 32984852; PubMed Central PMCID: PMC7518512.
• Brannvoll A*, Xue X*, Kwon Y, Kompocholi S, Simonsen AKW, Viswalingam KS, Gonzalez L, Hickson ID, Oestergaard VH, Mankouri HW, Sung P, Lisby M. The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells. Cell Rep. 2020 Jul 7;32(1):107849. doi: 10.1016/j.celrep.2020.107849. PubMed PMID: 32640219; NIHMSID:NIHMS1623395.
• Pérez-Calero C, Bayona-Feliu A, Xue X, Barroso SI, Muñoz S, González-Basallote VM, Sung P, Aguilera A. UAP56/DDX39B is a major cotranscriptional RNA-DNA helicase that unwinds harmful R loops genome-wide. Genes Dev. 2020 Jul 1;34(13-14):898-912. doi: 10.1101/gad.336024.119. Epub 2020 May 21. PubMed PMID: 32439635; PubMed Central PMCID: PMC7328515.
• Daley JM, Tomimatsu N, Hooks G, Wang W, Miller AS, Xue X, Nguyen KA, Kaur H, Williamson E, Mukherjee B, Hromas R, Burma S, Sung P.Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions. Nat Commun. 2020 Jun 18;11(1):3088. doi: 10.1038/s41467-020-16903-4. PubMed PMID: 32555206; PubMed Central PMCID: PMC7303207.

2019

• Xue C, Daley JM, Xue X, Steinfeld J, Kwon Y, Sung P, Greene EC. Single-molecule visualization of human BLM helicase as it acts upon double- and single-stranded DNA substrates. Nucleic Acids Res. 2019 Dec 2;47(21):11225-11237. doi: 10.1093/nar/gkz810. PubMed PMID: 31544923; PubMed Central PMCID: PMC6868385.
• Jiang H, Xue X, Panda S, Kawale A, Hooy RM, Liang F, Sohn J, Sung P, Gekara NO. Chromatin-bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death. EMBO J. 2019 Oct 4;38(21):e102718. doi: 10.15252/embj.2019102718. Epub 2019 Sep 23. PubMed PMID: 31544964; PubMed Central PMCID: PMC6826206.

2018

• Wang W, Daley JM, Kwon Y, Xue X, Krasner DS, Miller AS, Nguyen KA, Williamson EA, Shim EY, Lee SE, Hromas R, Sung P. A DNA nick at Ku-blocked double-strand break ends serves as an entry site for exonuclease 1 (Exo1) or Sgs1-Dna2 in long-range DNA end resection. J Biol Chem. 2018 Nov 2;293(44):17061-17069. doi: 10.1074/jbc.RA118.004769. Epub 2018 Sep 17. PubMed PMID: 30224356; PubMed Central PMCID: PMC6222114.
• Li T, Zhao Q, Yang X, Chen C, Yang K, Wu C, Zhang T, Duan Y, Xue X, Mi K, Ji X, Wang Z, Yang H. Structural insight into the Zika virus capsid encapsulating the viral genome. Cell Res. 2018 Apr;28(4):497-499. doi: 10.1038/s41422-018-0007-9. Epub 2018 Feb 21. PubMed PMID: 29467384; PubMed Central PMCID: PMC5939043.

2017

• Daley JM, Jimenez-Sainz J, Wang W, Miller AS, Xue X, Nguyen KA, Jensen RB, Sung P. Enhancement of BLM-DNA2-Mediated Long-Range DNA End Resection by CtIP. Cell Rep. 2017 Oct 10;21(2):324-332. doi: 10.1016/j.celrep.2017.09.048. PubMed PMID: 29020620; PubMed Central PMCID: PMC5689478.
• Miller AS, Daley JM, Pham NT, Niu H, Xue X, Ira G, Sung P. A novel role of the Dna2 translocase function in DNA break resection. Genes Dev. 2017 Mar 1;31(5):503-510. doi: 10.1101/gad.295659.116. Epub 2017 Mar 23. PubMed PMID: 28336516; PubMed Central PMCID: PMC5393064.

2016

• Bonner JN, Choi K, Xue X, Torres NP, Szakal B, Wei L, Wan B, Arter M, Matos J, Sung P, Brown GW, Branzei D, Zhao X. Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates. Cell Rep. 2016 Jul 12;16(2):368-378. doi: 10.1016/j.celrep.2016.06.015. Epub 2016 Jun 30. PubMed PMID: 27373152; PubMed Central PMCID: PMC5051638.
• Xue X, Papusha A, Choi K, Bonner JN, Kumar S, Niu H, Kaur H, Zheng XF, Donnianni RA, Lu L, Lichten M, Zhao X, Ira G, Sung P. Differential regulation of the anti-crossover and replication fork regression activities of Mph1 by Mte1. Genes Dev. 2016 Mar 15;30(6):687-99. doi: 10.1101/gad.276139.115. Epub 2016 Mar 10. PubMed PMID: 26966246; PubMed Central PMCID: PMC4803054.

2015

• Xue X, Sung P, Zhao X. Functions and regulation of the multitasking FANCM family of DNA motor proteins. Genes Dev. 2015 Sep 1;29(17):1777-88. doi: 10.1101/gad.266593.115. Review. PubMed PMID: 26341555; PubMed Central PMCID: PMC4573851.
• Xue X*, Choi K*, Bonner JN, Szakal B, Chen YH, Papusha A, Saro D, Niu H, Ira G, Branzei D, Sung P, Zhao X. Selective modulation of the functions of a conserved DNA motor by a histone fold complex. Genes Dev. 2015 May 15;29(10):1000-5. doi: 10.1101/gad.259143.115. Epub 2015 May 8. PubMed PMID: 25956905; PubMed Central PMCID: PMC4441048.

2014

• Zhao Q*, Xue X*, Longerich S*, Sung P, Xiong Y. Structural insights into 5′ flap DNA unwinding and incision by the human FAN1 dimer. Nat Commun.2014 Dec 11;5:5726. doi: 10.1038/ncomms6726. PubMed PMID: 25500724; PubMed Central PMCID: PMC4268874.
• Xue X, Choi K, Bonner J, Chiba T, Kwon Y, Xu Y, Sanchez H, Wyman C, Niu H, Zhao X, Sung P. Restriction of replication fork regression activities by a conserved SMC complex. Mol Cell. 2014 Nov 6;56(3):436-45. doi: 10.1016/j.molcel.2014.09.013. Epub 2014 Oct 16. PubMed PMID: 25439736; PubMed Central PMCID: PMC4268010.
• Daley JM, Chiba T, Xue X, Niu H, Sung P. Multifaceted role of the Topo IIIα-RMI1-RMI2 complex and DNA2 in the BLM-dependent pathway of DNA break end resection. Nucleic Acids Res. 2014;42(17):11083-91. doi: 10.1093/nar/gku803. Epub 2014 Sep 8. PubMed PMID: 25200081; PubMed Central PMCID: PMC4176181.

2013

• Xue X, Raynard S, Busygina V, Singh AK, Sung P. Role of replication protein A in double holliday junction dissolution mediated by the BLM-Topo IIIα-RMI1-RMI2 protein complex. J Biol Chem. 2013 May 17;288(20):14221-7. doi: 10.1074/jbc.M113.465609. Epub 2013 Mar 30. PubMed PMID: 23543748; PubMed Central PMCID: PMC3656278.

2012

• Daee DL, Ferrari E, Longerich S, Zheng XF, Xue X, Branzei D, Sung P, Myung K. Rad5-dependent DNA repair functions of the Saccharomyces cerevisiae FANCM protein homolog Mph1. J Biol Chem. 2012 Aug 3;287(32):26563-75. doi: 10.1074/jbc.M112.369918. Epub 2012 Jun 12. PubMed PMID: 22696213; PubMed Central PMCID: PMC3410997.
• Tsai SP, Su GC, Lin SW, Chung CI, Xue X, Dunlop MH, Akamatsu Y, Jasin M, Sung P, Chi P. Rad51 presynaptic filament stabilization function of the mouse Swi5-Sfr1 heterodimeric complex. Nucleic Acids Res. 2012 Aug;40(14):6558-69. doi: 10.1093/nar/gks305. Epub 2012 Apr 9. PubMed PMID: 22492707; PubMed Central PMCID: PMC3413116.

2011

• Hohl M, Kwon Y, Galván SM, Xue X, Tous C, Aguilera A, Sung P, Petrini JH. The Rad50 coiled-coil domain is indispensable for Mre11 complex functions. Nat Struct Mol Biol. 2011 Sep 4;18(10):1124-31. doi: 10.1038/nsmb.2116. PubMed PMID: 21892167; PubMed Central PMCID: PMC3190017.

2008

• Xue X*, Yu H*, Yang H, Xue F, Wu Z, Shen W, Li J, Zhou Z, Ding Y, Zhao Q, Zhang XC, Liao M, Bartlam M, Rao Z. Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design. J Virol. 2008 Mar;82(5):2515-27. doi: 10.1128/JVI.02114-07. Epub 2007 Dec 19. PubMed PMID: 18094151; PubMed Central PMCID: PMC2258912.
• Bartlam M, Xue X, Rao Z. The search for a structural basis for therapeutic intervention against the SARS coronavirus. Acta Crystallogr A. 2008 Jan;64(Pt 1):204-13. doi: 10.1107/S0108767307054426. Epub 2007 Dec 21. PubMed PMID: 18156685; PubMed Central PMCID: PMC7161629.

2007

• Xue X*, Yang H*, Shen W, Zhao Q, Li J, Yang K, Chen C, Jin Y, Bartlam M, Rao Z. Production of authentic SARS-CoV M(pro) with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction. J Mol Biol. 2007 Feb 23;366(3):965-75. doi: 10.1016/j.jmb.2006.11.073. Epub 2006 Dec 1. PubMed PMID: 17189639; PubMed Central PMCID: PMC7094453.

2006

• Liang W, Yang H, Xue X, Huang Q, Bartlam M, Chen S. Expression, crystallization and preliminary X-ray studies of the immunoglobulin-like domain 3 of human palladin. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jun 1;62(Pt 6):556-8. doi: 10.1107/S1744309106016411. Epub 2006 May 31. PubMed PMID: 16754980; PubMed Central PMCID: PMC2243106.

2005

• Yang H, Xie W, Xue X, Yang K, Ma J, Liang W, Zhao Q, Zhou Z, Pei D, Ziebuhr J, Hilgenfeld R, Yuen KY, Wong L, Gao G, Chen S, Chen Z, Ma D, Bartlam M, Rao Z. Design of wide-spectrum inhibitors targeting coronavirus main proteases. PLoS Biol. 2005 Oct;3(10):e324. doi: 10.1371/journal.pbio.0030324. Epub 2005 Sep 6. PubMed PMID: 16128623; PubMed Central PMCID: PMC1197287.

2004

• Yang HT, Wu DH, Xue XY, Liang WX, Miao XY, Pang H, Chen SJ. Cloning, expression, purification and crystallization of NHR3 domain from acute myelogenous leukemia-related protein AML1-ETO. Acta Biochim Biophys Sin (Shanghai). 2004 Aug;36(8):566-70. doi: 10.1093/abbs/36.8.566. PubMed PMID: 15295650.

* co-first author,       # co-corresponding author

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